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Several studies include a standard-of-care arm measuring wound size, duration of wound, healing time in days to complete epithelization, patient characteristics, and many complications and adverse events.22-35 In a literature review, the healing time for standard-of-care wet-to-moist dressing changes was an average of 53.324.5 days, which is a difference of 18 days compared with negative pressure wound therapy (35.117.2 days).22-35 New Horizons: Biologics In recent years, bioscaffold material has shown promising tissue regenerative properties

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